2-Methyl-1,3-benzoxazole-6-carboxylic acid - Names and Identifiers
Name | 2-Methyl-1,3-benzoxazole-6-carboxylic acid
|
Synonyms | 1,2-Ethanediamine,5-phenyl- 2-Methylbenzoxazole-6-carboxylic Acid 2-Methyl-6-benzoxazole carboxylic acid 6-Benzoxazolecarboxylic acid, 2-methyl- 2-METHYLBENZO[D]OXAZOLE-6-CARBOXYLIC ACID 2-Methyl-1,3-benzoxazole-6-carboxylic acid Benzenepropanoicacid,7-methyl-β-oxo-,ethylester
|
CAS | 13452-14-7
|
InChI | InChI=1/C9H7NO3/c1-5-10-7-3-2-6(9(11)12)4-8(7)13-5/h2-4H,1H3,(H,11,12) |
2-Methyl-1,3-benzoxazole-6-carboxylic acid - Physico-chemical Properties
Molecular Formula | C9H7NO3
|
Molar Mass | 177.16 |
Density | 1.38g/cm3 |
Melting Point | >230°C (dec.) |
Boling Point | 353.462°C at 760 mmHg |
Flash Point | 167.568°C |
Solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | Pale Beige |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.64 |
MDL | MFCD07787266 |
2-Methyl-1,3-benzoxazole-6-carboxylic acid - Introduction
2-methyl -1, 3-benzoxazole-6-carboxylic acid is an organic compound with the formula C10H7NO3. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 2-methyl -1, 3-benzoxazole-6-carboxylic acid is colorless crystal or solid powder.
-Solubility: It is almost insoluble in water, but has good solubility in organic solvents such as ethanol, dimethyl sulfoxide, etc.
Use:
-Chemical synthesis: 2-methyl -1, 3-benzoxazole-6-carboxylic acid can be used as an intermediate in organic synthesis and is widely used in pesticide, medicine and dye industries.
-Pesticide: It can be used as a synthetic raw material for ciprofloxacin and other fungicides and herbicides, and has good antibacterial and insecticidal activity.
-Medicine: 2-methyl -1, 3-benzoxazole-6-carboxylic acid has certain inhibitory effects on cell growth and DNA replication, so it may have potential applications in drug development.
-Dye: It can be used as a synthetic intermediate for organic dyes and used in the dye industry.
Preparation Method:
- 2-methyl -1,3-benzoxazole -6-carboxylic acid synthesis method is more, common methods include: benzoxazole derivatives with methylating reagent reaction, or through the methyl diamine acid and hydroxyl compounds with condensation reaction. The specific synthetic route will vary depending on the desired product and reaction conditions.
Safety Information:
- 2-methyl -1, 3-benzoxazole-6-carboxylic acid has low toxicity, but it is still necessary to pay attention to safe operation.
-When using, avoid direct contact with the skin and avoid inhaling its dust and vapor.
-Observe relevant safety regulations during handling and storage, such as wearing personal protective equipment (e. g. gloves, goggles, etc.).
-If taken by mistake or inhaled, seek medical attention immediately. Any abnormal condition after contact with chemicals should seek medical help immediately.
Last Update:2024-04-09 19:05:46